Amoebiasis cutis in HIV positive patient

Indian J Dermatol Venereol Leprol. May-Jun 2006;72(3):224-6. doi: 10.4103/0378-6323.25786.

Abstract

Protozoan infections of the skin, particularly cutaneous amoebiasis, are rare in HIV-positive patients. We report a case of amoebiasis cutis in an HIV-positive truck driver with a history of frequent unprotected sexual exposures. He presented with multiple painful ulcers and sinuses with purulent discharge, necrotic slough and scarring in the perianal and gluteal region for the last 2 years. He was positive for HIV-1 and -2. Cutaneous biopsy revealed numerous Entamoeba histolytica in the trophozoite form, in addition to an inflammatory infiltrate and necrotic debris. He responded well to oral metronidazole and chloroquine. Amoebiasis cutis should be considered in the differential diagnosis of perianal ulcers, particularly in HIV-positive patients.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Amebiasis / drug therapy*
  • Amebiasis / parasitology*
  • Amebiasis / pathology
  • Amebicides / therapeutic use
  • Animals
  • Antiprotozoal Agents / therapeutic use
  • Anus Diseases / drug therapy
  • Anus Diseases / parasitology*
  • Anus Diseases / pathology*
  • Chloroquine / therapeutic use
  • Entamoeba histolytica / pathogenicity
  • Entamoebiasis / drug therapy
  • Entamoebiasis / parasitology
  • Entamoebiasis / pathology
  • Humans
  • Male
  • Metronidazole / therapeutic use
  • Treatment Outcome
  • Ulcer / drug therapy
  • Ulcer / parasitology
  • Ulcer / pathology

Substances

  • Amebicides
  • Antiprotozoal Agents
  • Metronidazole
  • Chloroquine