Case report: We present the case of 54-year-old male who developed bilateral cystoid macular thickening while taking 3 g of niacin per day, and we describe the optical coherence tomography (OCT) features of niacin (nicotinic acid) maculopathy.
Comments: Cystoid spaces were seen in both the outer plexiform and inner nuclear layers of both eyes. The cystoid spaces were largest and central in the outer plexiform layer, whereas a broader distribution of smaller cysts was seen in the inner nuclear layer. With cessation of niacin, his vision improved and the OCT features normalized.