Surgical intervention in patients with moderate to severe pulmonary arterial hypertension

Conn Med. 2006 Apr;70(4):239-43.


Background: Patients with pulmonary arterial hypertension are believed to experience severe postoperative complications after major surgery.

Methods: We retrospectively analyzed the data of 21 patients with pulmonary arterial hypertension who underwent 28 surgical procedures at our institution between 1996 and 2002.

Results: The average mean pulmonary arterial pressure was 53 +/- 14.4 mm Hg. Twenty-two procedures were performed under general anesthesia. Extubation occurred within 24 hours of surgery in 72% and an intensive care unit stay was not required after 43% of the procedures. Perioperative morbidity and mortality were typically related to the surgical procedure or underlying disease.

Conclusions: In our study, patients with moderate to severe pulmonary arterial hypertension had an 18% per procedure mortality and a 19% rate of right heart failure after surgical intervention.

MeSH terms

  • Adult
  • Aged
  • Anesthesia, General
  • Female
  • Humans
  • Hypertension, Pulmonary / complications*
  • Hypertension, Pulmonary / surgery
  • Male
  • Middle Aged
  • Ohio
  • Postoperative Complications / epidemiology*
  • Postoperative Complications / mortality
  • Retrospective Studies
  • Risk Assessment
  • Risk Factors