Pulmonary agenesis--vascular airway compression and gastroesophageal reflux influence outcome

J Pediatr Surg. 2006 Jun;41(6):1165-9. doi: 10.1016/j.jpedsurg.2006.02.012.


Pulmonary agenesis (PA) is a rare malformation that can be isolated or associated with other anomalies. We report 3 cases of left-sided PA having ipsilateral renal agenesis, facial, and radial ray anomalies. Patients presented in infancy with nonspecific respiratory symptoms and were diagnosed to have PA on chest radiograph and computed tomographic scan. Bronchial compression, by dilated pulmonary artery and associated severe gastroesophageal reflux, aggravated respiratory symptoms and required surgical intervention. The relevant literature is briefly reviewed.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Abnormalities, Multiple
  • Airway Obstruction / etiology*
  • Bronchial Diseases / etiology*
  • Dilatation, Pathologic / complications
  • Fundoplication
  • Gastroesophageal Reflux / etiology*
  • Gastroesophageal Reflux / surgery
  • Gastrostomy
  • Humans
  • Infant
  • Kidney / abnormalities
  • Lung / abnormalities*
  • Lung / diagnostic imaging
  • Lung / physiopathology
  • Male
  • Pulmonary Artery / abnormalities*
  • Radiography, Thoracic
  • Tomography, X-Ray Computed