Scedosporium Apiospermum: Changing Clinical Spectrum of a Therapy-Refractory Opportunist

Med Mycol. 2006 Jun;44(4):295-327. doi: 10.1080/13693780600752507.

Abstract

Current knowledge on the opportunist Scedosporium apiospermum (teleomorph: Pseudallescheria boydii), generated over a period of more than 120 years, is reviewed. The natural environmental habitat of the fungus is unknown; nutrient-rich, brackish waters like river estuaria have been suggested. The fungus is strongly promoted by agricultural and particularly by industrial pollution.

Publication types

  • Review

MeSH terms

  • Adolescent
  • Adult
  • Animals
  • Antifungal Agents / therapeutic use*
  • Cattle
  • Child
  • Child, Preschool
  • Dogs
  • Drug Resistance, Fungal*
  • Guinea Pigs
  • Humans
  • Mice
  • Mycetoma / drug therapy*
  • Mycetoma / epidemiology
  • Mycetoma / microbiology
  • Mycetoma / physiopathology*
  • Opportunistic Infections / drug therapy*
  • Opportunistic Infections / epidemiology
  • Opportunistic Infections / microbiology
  • Opportunistic Infections / physiopathology
  • Scedosporium / classification
  • Scedosporium / growth & development
  • Scedosporium / pathogenicity*

Substances

  • Antifungal Agents