Stent-graft treatment of infected aortic and arterial aneurysms

J Endovasc Ther. 2006 Jun;13(3):338-45. doi: 10.1583/05-1516.1.


Purpose: To evaluate the feasibility and effectiveness of endovascular stent-graft repair of infected aortic and arterial aneurysms.

Methods: Eight patients (5 men; mean age 56.6 years, range 30-85) with infected saccular aneurysms in the brachiocephalic artery (n=1), proximal descending thoracic aorta (n=1), infrarenal abdominal aorta (n=3), common iliac artery (n=1), and common femoral artery (n=2) were treated with stent-graft placement and intravenous antibiotic treatment for at least 6 weeks followed by case-specific administration of oral suppressive antibiotics. All patients were considered to be in the high-surgical-risk group.

Results: Exclusion of the infected aneurysm was successful in all patients. However, 2 patients died within 30 days of uncontrolled sepsis, and 1 patient died at 6 months after rupture of a persistently infected aneurysm (37% mortality rate). Over a follow-up that ranged to 8 years, the 5 survivors showed complete resolution of the infected aneurysms; no stent-graft infection was observed during follow-up.

Conclusion: The acceptable technical and clinical success of endovascular aneurysm repair makes this a promising treatment for infected aortic and arterial aneurysms. However, it is crucial that the infection is treated adequately prior to stent-graft placement.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Aneurysm, Infected / drug therapy
  • Aneurysm, Infected / mortality
  • Aneurysm, Infected / surgery*
  • Angioplasty*
  • Anti-Bacterial Agents / therapeutic use
  • Antibiotic Prophylaxis
  • Aortic Aneurysm, Abdominal / drug therapy
  • Aortic Aneurysm, Abdominal / mortality
  • Aortic Aneurysm, Abdominal / surgery*
  • Aortic Aneurysm, Thoracic / drug therapy
  • Aortic Aneurysm, Thoracic / mortality
  • Aortic Aneurysm, Thoracic / surgery*
  • Blood Vessel Prosthesis Implantation*
  • Feasibility Studies
  • Female
  • Follow-Up Studies
  • Humans
  • Iliac Aneurysm / drug therapy
  • Iliac Aneurysm / mortality
  • Iliac Aneurysm / surgery*
  • Male
  • Middle Aged
  • Retrospective Studies
  • Stents*
  • Treatment Outcome


  • Anti-Bacterial Agents