The levonorgestrel-releasing intrauterine device reduces CA-125 serum levels in patients with endometriosis

Fertil Steril. 2006 Sep;86(3):742-4. doi: 10.1016/j.fertnstert.2006.02.082. Epub 2006 Jun 19.


This study compared the long-term effects of the levonorgestrel-releasing intrauterine device with those of GnRH agonist administration on serum levels of CA-125 in patients with endometriosis. The levonorgestrel-releasing intrauterine device was found to be as efficient as GnRH agonist in reducing CA-125 serum levels.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adolescent
  • Adult
  • CA-125 Antigen / blood*
  • Contraceptive Agents, Female / administration & dosage
  • Endometriosis / blood*
  • Endometriosis / drug therapy*
  • Equipment Failure Analysis
  • Female
  • Humans
  • Intrauterine Devices, Medicated*
  • Levonorgestrel / administration & dosage*
  • Treatment Outcome


  • CA-125 Antigen
  • Contraceptive Agents, Female
  • Levonorgestrel