The mean platelet volume in gestational diabetes

J Thromb Thrombolysis. 2006 Aug;22(1):51-4. doi: 10.1007/s11239-006-8322-2.

Abstract

Objective: To compare the platelet count and mean platelet volume (MPV) values of pregnancies diagnosed with gestational diabetes with those of healthy pregnancies.

Material-method: Between June 2003 and September 2004, 100 healthy pregnancies and 100 pregnancies with gestational diabetes were studied at Gazi University, Department of Obstetrics and Gynecology.

Results: While no statistically significant difference was observed in the platelet count between the two groups, the MPV of the gestational diabetes group (9.4 +/- 1.6 fl) was evaluated to be significantly higher than the MPV of the healthy pregnancy group (8.3 +/- 1.1 fl). Additionally, when linear regression analysis was performed an inverse relationship was observed between platelet number and MPV.

Conclusion: There is a need for further research focusing on the platelet function in the observation and treatment of gestational diabetes, which can pose the risk of developing Type 2 diabetes for the mother and has negative consequences for the fetus.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Blood Platelets / cytology*
  • Chi-Square Distribution
  • Diabetes, Gestational / blood*
  • Female
  • Gestational Age
  • Humans
  • Infant, Newborn
  • Linear Models
  • Platelet Count*
  • Pregnancy