Viruses take center stage in cellular evolution

Genome Biol. 2006;7(6):110. doi: 10.1186/gb-2006-7-6-110.


The origins of viruses are shrouded in mystery, but advances in genomics and the discovery of highly complex giant DNA viruses have stimulated new hypotheses that DNA viruses were involved in the emergence of the eukaryotic cell nucleus, and that they are worthy of being considered as living organisms.

MeSH terms

  • Animals
  • Cell Nucleus / metabolism
  • Cell Nucleus / virology
  • DNA Viruses / genetics*
  • Eukaryotic Cells / virology*
  • Evolution, Molecular*
  • Genomics
  • Humans
  • Models, Biological