Clinical history in gastroesophageal cough

Respir Med. 2007 Feb;101(2):345-8. doi: 10.1016/j.rmed.2006.05.006. Epub 2006 Jun 19.


Gastroesophageal disease, a common cause of chronic cough, is often poorly recognised. We reviewed the presenting history of 47 chronic cough patients who had been proven to have gastroesophageal disease by oesophageal function testing. Fourty-seven patients (26 female), were enroled. Symptoms which were most common included: cough on phonation, on rising from bed, associated with certain foods or with eating in general. Symptoms known to be associated with laryngopharyngeal reflux, such as throat clearing, dysphonia, globus and dysphagia were also associated. Heartburn or indigestion was present in 63% of those questioned. These data show that symptoms associated with reflux in chronic coughers differ from those commonly perceived to be characteristic of classical heartburn-associated reflux. These data suggest that, contrary to previous reports, a symptom complex which is characteristic of reflux cough can be identified.

MeSH terms

  • Chronic Disease
  • Cough / etiology*
  • Cough / physiopathology
  • Female
  • Gastroesophageal Reflux / complications*
  • Gastroesophageal Reflux / physiopathology
  • Humans
  • Male
  • Middle Aged