The contribution of Bruce Glick to the definition of the role played by the bursa of Fabricius in the development of the B cell lineage

Clin Exp Immunol. 2006 Jul;145(1):1-4. doi: 10.1111/j.1365-2249.2006.03131.x.

Abstract

In 1956, Bruce Glick and Timothy Chang reported that the bursa of Fabricius plays an important role in antibody production. Their demonstration that antibody responses are suppressed in the majority of bursectomized chickens became the cornerstone of modern immunology. Bursa research increased considerably during the 1960s and early 1970s.

Publication types

  • Historical Article
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Allergy and Immunology / history*
  • Animals
  • Antibody Formation
  • B-Lymphocytes*
  • Bursa of Fabricius / immunology*
  • History, 16th Century
  • History, 20th Century
  • Humans