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. 2007 Mar;45(3):617-25.
doi: 10.1016/j.brat.2006.04.008. Epub 2006 Jun 23.

Treatment-resistant Depressed Patients Show a Good Response to Mindfulness-based Cognitive Therapy

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Treatment-resistant Depressed Patients Show a Good Response to Mindfulness-based Cognitive Therapy

M A Kenny et al. Behav Res Ther. .
Free PMC article


Mindfulness-based Cognitive Therapy (MBCT) is a class-based programme designed for use in the prevention of relapse of major depression. Its aim is to teach participants to disengage from those cognitive processes that may render them vulnerable to future episodes. These same cognitive processes are also known to maintain depression once established, hence a clinical audit was conducted to explore the use of MBCT in patients who were currently actively depressed, and who had not responded fully to standard treatments. The study showed that it was acceptable to these patients and resulted in an improvement in depression scores (pre-post Effect Size=1.04), with a significant proportion of patients returning to normal or near-normal levels of mood.


Fig. 1
Fig. 1
BDI scores pre and post MBCT.

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    1. Baer R.A. Mindfulness training as a clinical intervention: A conceptual and empirical review. Clinical Psychology: Science and Practice. 2003;10:125–143.
    1. Baldwin S.A., Murray D.M., Shadish W.R. Empirically supported treatment or type i errors? Problems with analysis of data from group administered treatment. Journal of Consulting and Clinical Psychology. 2005;73:924–935. - PubMed
    1. Beautrais A.L., Joyce P.R., Mulder R.T., Fergusson D.M., Deavoll B.J., Nightingale S.K. Prevalence and co-morbidity of mental disorders in persons making serious suicidal attempts: A case control study. American Journal of Psychiatry. 1996;153:1009–1014. - PubMed
    1. Beck A.T., Rush A.J., Shaw B.F., Emery G. Guilford Press; New York: 1979. Cognitive therapy of depression.
    1. Berti Ceroni G., Neri C., Pezzoli A. Chronicity in major depression. A naturalistic prospective study. Journal of Affective Disorders. 1984;7:123–132. - PubMed

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