High prevalence of multidrug resistance and random distribution of mobile genetic elements among uropathogenic Escherichia coli (UPEC) of the four major phylogenetic groups

Curr Microbiol. 2006 Aug;53(2):158-62. doi: 10.1007/s00284-005-0501-4. Epub 2006 Jun 26.

Abstract

One hundred and ten UTI Escherichia coli strains, from Ljubljana, Slovenia, were analyzed for antibiotic resistances, mobile DNA elements, serotype, and phylogenetic origin. A high prevalence of drug resistance and multidrug resistance was found. Twenty-six percent of the isolates harbored a class 1 integron, while a majority of the strains (56%) harbored rep sequences characteristic of F-like plasmids. int as well as rep sequences were found to be distributed in a random manner among strains of the four major phylogenetic groups indicating that all groups have a similar tendency to acquire and maintain mobile genetic elements frequently associated with resistance determinants.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Conjugation, Genetic
  • Drug Resistance, Multiple / genetics*
  • Escherichia coli / classification
  • Escherichia coli / drug effects
  • Escherichia coli / genetics*
  • Escherichia coli / pathogenicity
  • Escherichia coli Infections / microbiology
  • Integrons
  • Interspersed Repetitive Sequences*
  • Phylogeny
  • Plasmids
  • Replicon
  • Serotyping
  • Slovenia
  • Urinary Tract Infections / microbiology