Empyema thoracis due to Rhizopus oryzae in an allogenic bone marrow transplant recipient

Med Mycol. 2006 Feb;44(1):75-8. doi: 10.1080/13693780500148392.


We describe a case of empyema thoracis caused by Rhizopus oryzae diagnosed in an allogenic bone marrow transplant patient with acute lymphocytic leukemia. The isolate of R. oryzae was recovered from three pleural effusion specimens, which were black in color. It was identified on the basis of characteristic colonial appearance and microscopic findings, as well as the partial sequencing of rRNA genes. The patient died of uncontrolled R. oryzae empyema thoracis and concomitant nosocomial infection.

Publication types

  • Case Reports

MeSH terms

  • Bone Marrow Transplantation
  • DNA, Fungal / chemistry
  • DNA, Fungal / genetics
  • DNA, Ribosomal / chemistry
  • DNA, Ribosomal / genetics
  • Empyema, Pleural / microbiology*
  • Humans
  • Male
  • Middle Aged
  • Mucormycosis / microbiology*
  • Pleural Effusion / microbiology
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / complications*
  • Radiography, Thoracic
  • Rhizopus / cytology
  • Rhizopus / genetics
  • Rhizopus / isolation & purification*
  • Sequence Analysis, DNA
  • Tomography, X-Ray Computed
  • Transplantation, Homologous


  • DNA, Fungal
  • DNA, Ribosomal