Reversible interconversion between a supramolecular polymer and a discrete octameric species from a guanosine derivative by dynamic cation binding and release

Org Lett. 2006 Jul 6;8(14):3125-8. doi: 10.1021/ol061115w.


[reaction: see text] The tunable interconversion between two highly ordered supramolecular motifs (G-quartet K(+)-templated column and G-ribbon) of a lipophilic guanosine derivative fueled by cation complexation and release in a cryptand [2.2.2] containing guanosine solution is reported. The process is controlled by the sequential addition of acid and base.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cations / chemistry
  • Guanosine / analogs & derivatives*
  • Guanosine / chemistry*
  • Models, Molecular*
  • Molecular Structure
  • Polymers / chemistry*


  • Cations
  • Polymers
  • Guanosine