One perfect worm

Trends Genet. 2006 Aug;22(8):405-7. doi: 10.1016/j.tig.2006.06.001. Epub 2006 Jun 27.


Recent studies show that local populations of the nematode Caenorhabditis elegans possess nearly as much genetic variation as that seen in existing worldwide collections. This suggests either wide-ranging migration and intense natural selection or recent dispersal, perhaps by human association. Either way, the effective population size of this ubiquitous model organism is unexpectedly small.

MeSH terms

  • Animals
  • Caenorhabditis / genetics*
  • Caenorhabditis elegans / genetics
  • Evolution, Molecular*
  • Genetic Variation*
  • Genetics, Population
  • Linkage Disequilibrium*
  • Polymorphism, Single Nucleotide*
  • RNA Interference / physiology