Statement of the problem

Am J Cardiol. 2006 Jun 19;97(12A):3G-8G. doi: 10.1016/j.amjcard.2006.02.022. Epub 2006 Apr 7.


The Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) study poses 2 questions. Of the options in treating the hyperglycemia of type 2 diabetes mellitus, which, if either, would be best for decreasing the likelihood of death or a serious cardiovascular disease event such as a heart attack: correcting the relative insulin deficiency or reducing insulin resistance? Do individuals with diabetes whose coronary disease can be managed medically have a better outcome with initial medical or interventional (percutaneous intervention or coronary artery bypass grafting) treatment? This article outlines the reasons for asking these questions.

MeSH terms

  • Angioplasty, Balloon, Coronary
  • Coronary Artery Bypass
  • Coronary Artery Disease / complications
  • Coronary Artery Disease / therapy*
  • Diabetes Mellitus, Type 1 / complications
  • Diabetes Mellitus, Type 1 / therapy*
  • Humans
  • Myocardial Revascularization
  • Randomized Controlled Trials as Topic*
  • Research Design