Treatment of reflux laryngopharyngitis with modified banxia xiexin tang (Pinellia decoction for draining the heart)--a report of 40 cases

J Tradit Chin Med. 2006 Jun;26(2):127-31.


Objective: To evaluate the effect of modified banxia xiexin tang ([Chinese characters: see text] Pinellia Decoction for Draining the Heart) in treatment of laryngopharyngitis caused by gastroesophageal reflux disease (GERD).

Methods: Forty patients in the treatment group were treated with modified Pinellia Decoction for Draining the Heart and 38 patients in the control group were treated with Jinsang Liyan Wan ([Chinese characters: see text] Pills for a Good Voice by Relieving Sore-Throat). The effects were evaluated by the improvement in symptoms and the parameters obtained in a grading system of gastroscopy and laryngoscopy.

Results and conclusion: The comparison of therapeutic effects on complication of laryngopharyngitis, GERD symptoms, and findings in gastroscope grading and laryngoscope (P < 0.05 or P < 0.01) demonstrated that the modified Pinellia Decoction for Draining the Heart was much more effective in treating laryngopahryngitis caused by gastroesophageal reflux.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Drugs, Chinese Herbal / therapeutic use*
  • Female
  • Gastroesophageal Reflux / complications*
  • Gastroesophageal Reflux / drug therapy
  • Humans
  • Male
  • Middle Aged
  • Pharyngitis / drug therapy*
  • Pinellia / chemistry*


  • Drugs, Chinese Herbal