[Case report: congenital myoclonus in a German Holstein calf]

Dtsch Tierarztl Wochenschr. 2006 May;113(5):203-6.
[Article in German]

Abstract

A female German Holstein calf was not able to stand up after birth. Resting the animal was lying in normal position and could lift its head. Sensory stimuli like auditory or tactile impulses induced myoclonic jerking of the whole body. Afterwards it calmed down quickly. The signs observed correspond to the clinical findings of congenital myoclonus in poll Hereford calves. The pathological examination revealed no indications for changes in organs. The inbreeding coefficient of the calf was 1.56 %. The present type of congenital myoclonus in the calf examined is likely to be genetically determined, even if the point mutation in exon 2 of the glycin receptor alpha 1 gene was not confirmed.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Animals
  • Animals, Newborn
  • Cattle
  • Cattle Diseases / congenital*
  • Cattle Diseases / genetics
  • Cattle Diseases / pathology
  • Codon / chemistry
  • Codon / genetics
  • DNA Primers / chemistry
  • Female
  • Inbreeding
  • Myoclonus / congenital
  • Myoclonus / genetics
  • Myoclonus / pathology
  • Myoclonus / veterinary*
  • Pedigree
  • Polymerase Chain Reaction / veterinary

Substances

  • Codon
  • DNA Primers