Abstract
A TRP family cation channel has been found to be critical for proprioception in the nematode Caenorhabditis elegans. This is a starting point for understanding conserved mechanotransduction mechanisms in proprioceptor neurons, and for deciphering how sensory feedback can function within a defined neural circuit to produce coordinated patterns of motor activity.
MeSH terms
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Alleles
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Animals
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Caenorhabditis elegans / genetics
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Caenorhabditis elegans / metabolism*
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Caenorhabditis elegans / physiology
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Caenorhabditis elegans Proteins / genetics
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Caenorhabditis elegans Proteins / metabolism
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Caenorhabditis elegans Proteins / physiology*
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Gene Deletion
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Interneurons / metabolism
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Locomotion / genetics
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Locomotion / physiology
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Proprioception / genetics
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Proprioception / physiology*
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TRPC Cation Channels / genetics
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TRPC Cation Channels / metabolism
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TRPC Cation Channels / physiology*
Substances
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Caenorhabditis elegans Proteins
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TRP-4 channel, C elegans
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TRPC Cation Channels