Moraxella keratitis: predisposing factors and clinical review of 95 cases

Br J Ophthalmol. 2006 Oct;90(10):1236-8. doi: 10.1136/bjo.2006.095182. Epub 2006 Jul 6.

Abstract

Aim: To analyse the clinical presentation, identify predisposing risk factors and evaluate the outcome of treatment of Moraxella keratitis.

Methods: A retrospective analysis was carried out of culture-proved cases of Moraxella keratitis from hospital records during a 10-year period (from December 1995 to November 2005) at the Corneal Unit of the Royal Victorian Eye and Ear Hospital, Melbourne, Australia.

Results: 95 episodes of Moraxella keratitis were identified in 92 patients. 3 (3.2%) patients had recurrent keratitis. The mean age of the patients was 70 (range 17-93) years. Multiple predisposing factors were identified in 23 (24%) eyes, including corneal graft (n = 15), previous herpes keratitis (n = 15) and eye lid diseases (n = 15). Adjunctive procedures were carried out in 42 eyes. These included botulinum toxin injection (n = 17), tarsorraphy (n = 12), penetrating keratoplasty (n = 8), enucleation (n = 3), tissue adhesive and bandage contact lens (n = 4), and conjunctival flap (n = 5). Polymicrobial infection was present in 17 eyes. Final visual acuity was counting finger or less in 25 (26%) eyes.

Conclusions: Local ocular predisposing factors play a major role in Moraxella keratitis. This infection has a poor visual outcome attributable to both the nature of the infection and the predisposing factors.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Corneal Ulcer / etiology*
  • Corneal Ulcer / microbiology
  • Corneal Ulcer / therapy
  • Eye Infections, Bacterial / etiology*
  • Eye Infections, Bacterial / microbiology
  • Eye Infections, Bacterial / therapy
  • Female
  • Humans
  • Male
  • Microbial Sensitivity Tests
  • Middle Aged
  • Moraxella*
  • Moraxellaceae Infections / etiology*
  • Moraxellaceae Infections / therapy
  • Recurrence
  • Retrospective Studies
  • Risk Factors
  • Treatment Outcome