Perception of emotional speech in Parkinson's disease

Mov Disord. 2006 Oct;21(10):1774-8. doi: 10.1002/mds.21038.

Abstract

Nonmotor symptoms in Parkinson's disease (PD) involving cognition and emotionality have progressively received attention. The objective of the present study was to investigate recognition of emotional prosody in patients with PD (n = 14) in comparison to healthy control subjects (HC, n = 14). Event-related brain potentials (ERP) were recorded in a modified oddball paradigm under passive listening and active target detection instructions. Results showed a poorer performance of PD patients in classifying emotional prosody. ERP generated by emotional deviants (happy/sad) during passive listening revealed diminished amplitudes of the mismatch-related negativity for sad deviants, indicating an impairment of early preattentive processing of emotional prosody in PD.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Attention / physiology
  • Cerebral Cortex / physiopathology
  • Comprehension
  • Contingent Negative Variation
  • Electroencephalography*
  • Emotions / physiology*
  • Evoked Potentials, Auditory / physiology
  • Female
  • Humans
  • Male
  • Middle Aged
  • Parkinson Disease / diagnosis
  • Parkinson Disease / physiopathology*
  • Reaction Time / physiology
  • Signal Processing, Computer-Assisted
  • Speech Acoustics*
  • Speech Perception / physiology*