Parkinson's disease, macular degeneration and cutaneous signs of mercury toxicity

J Occup Environ Med. 2006 Jul;48(7):656. doi: 10.1097/01.jom.0000228351.74230.52.


Objective: The objective of this study was to determined if there was a relationship between Grover's disease and Parkinson disease.

Methods: Fourteen patients with Parkinson disease and 14 control patients were randomly selected and examined for cutaneous eruptions and blood mercury levels.

Results: Of the 14 patients with Parkinson's disease, 13 had Grover's disease and detectable blood mercury. None of the patients in the control group had a cutaneous eruption and only 2of the 14 had detectable blood mercury.

Conclusion: Mercury may play a role in the etiology of Parkinson disease and Grover's disease.

Publication types

  • Letter

MeSH terms

  • Cross-Sectional Studies
  • Humans
  • Macular Degeneration / etiology*
  • Mercury Poisoning / complications*
  • Mercury Poisoning / diagnosis
  • Occupational Exposure*
  • Parkinson Disease / etiology*
  • Silicon Dioxide
  • United States


  • Silicon Dioxide