[Determination of trace elements in cerebrospinal fluid (CSF) of patients suffering cerebrovascular disease by atomic absorption spectrometry]

Guang Pu Xue Yu Guang Pu Fen Xi. 2006 Apr;26(4):720-2.
[Article in Chinese]


The contents of some trace elements such as zinc, copper, iron and cadmium in cerebrospinal fluid (CSF) of normal persons and the patients who suffered cerebral hemorrhage or infarction were determined directly by atomic absorption spectrometry. The method is simple and convenient with a recovery ratio by standard addition being 97.6% to 104.8%, and a relative standard deviation (RSD) is lower than 5%. The test showed that except for the content copper lower than normal, the patients suffering cerebrovascular disease have much higher contents of zinc, iron and cadmium. The result provides useful data for studying the relation between the contents of these trace elements and cerebrovascular disease, as well as diagnosing, treating and preventing this disease.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Cadmium / analysis
  • Cerebrovascular Disorders / cerebrospinal fluid*
  • Cerebrovascular Disorders / diagnosis
  • Copper / cerebrospinal fluid
  • Female
  • Humans
  • Iron / cerebrospinal fluid
  • Male
  • Middle Aged
  • Spectrophotometry, Atomic / methods*
  • Trace Elements / cerebrospinal fluid*
  • Zinc / cerebrospinal fluid


  • Trace Elements
  • Cadmium
  • Copper
  • Iron
  • Zinc