Palladium-catalyzed oxidation of Boc-protected N-methylamines with IOAc as the oxidant: a Boc-directed sp3 C-H bond activation

Dong-Hui Wang; Xue-Shi Hao; Di-Fu Wu; Jin-Quan Yu

doi:10.1021/ol061384m

Palladium-catalyzed oxidation of Boc-protected N-methylamines with IOAc as the oxidant: a Boc-directed sp3 C-H bond activation

Org Lett. 2006 Jul 20;8(15):3387-90. doi: 10.1021/ol061384m.

Authors

Dong-Hui Wang¹, Xue-Shi Hao, Di-Fu Wu, Jin-Quan Yu

Affiliation

¹ Department of Chemistry MS015, Brandeis University, Waltham, Massachusetts 02454-9110, USA.

PMID: 16836412
DOI: 10.1021/ol061384m

Abstract

[Structure: see text] Pd-catalyzed selective oxidation of Boc-protected N-methylamines with IOAc as the oxidant is described. Evidence for the involvement of a Boc-directed C-H activation process is provided.