Prevalence of erm genes encoding macrolide-lincosamide-streptogramin (MLS) resistance among clinical isolates of Staphylococcus aureus in a Turkish university hospital

Clin Microbiol Infect. 2006 Aug;12(8):797-9. doi: 10.1111/j.1469-0691.2006.01486.x.

Abstract

This study investigated the prevalence of the erm(A), erm(B) and erm(C) genes among 122 MLS-resistant clinical isolates of Staphylococcus aureus from a Turkish university hospital. Of these isolates, 44 were inducibly resistant and 78 were constitutively resistant. The presence of one or more erm genes was demonstrated in 114 isolates; the erm(C) gene was detected in 97 isolates, and the erm(A) gene was detected in 96 isolates. Seventy-eight isolates harboured both erm(A) and erm(C). The combination of erm(A), erm(B) and erm(C) genes was detected in only one isolate.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacterial Proteins / genetics*
  • Drug Resistance, Multiple, Bacterial
  • Hospitals, University
  • Humans
  • Lincosamides
  • Macrolides / pharmacology
  • Methyltransferases / genetics*
  • Staphylococcus aureus / drug effects*
  • Staphylococcus aureus / genetics*
  • Streptogramin Group B / pharmacology

Substances

  • Bacterial Proteins
  • Lincosamides
  • Macrolides
  • Streptogramin Group B
  • Methyltransferases
  • ErmA protein, Bacteria