Common scaffolds, diverse recognition profiles

Structure. 2006 Jul;14(7):1093-4. doi: 10.1016/j.str.2006.06.001.

Abstract

A paper in this issue of Structure reports the crystal structure of griffithsin, a lectin from red algae, and demonstrates its ability to bind and neutralize the SARS coronavirus, providing a link in understanding the evolution of lectins in this family. (Ziółkowska et al., 2006).

Publication types

  • News
  • Comment

MeSH terms

  • Algal Proteins / chemistry*
  • Algal Proteins / genetics
  • Algal Proteins / pharmacology*
  • Animals
  • Crystallography
  • Evolution, Molecular*
  • Lectins / chemistry*
  • Lectins / genetics
  • Plant Lectins
  • Protein Conformation
  • Severe acute respiratory syndrome-related coronavirus / drug effects*

Substances

  • Algal Proteins
  • Lectins
  • Plant Lectins
  • griffithsin protein, Griffithsia