Quality of life in patients with chronic obstructive pulmonary disease and comorbid anxiety or depression

Psychosomatics. 2006 Jul-Aug;47(4):312-9. doi: 10.1176/appi.psy.47.4.312.


The authors examined 179 veterans with chronic obstructive pulmonary disease (COPD) to determine the relative contribution of clinical depression and/or anxiety (Beck Depression and Beck Anxiety Inventories) to their quality of life (Chronic Respiratory Questionnaire and Medical Outcomes Survey Short Form). Multiple-regression procedures found that both depression and anxiety were significantly related to negative quality-of-life outcomes (anxiety with both mental and physical health quality-of-life outcomes, and depression primarily with mental health). When comorbid with COPD, mental health symptoms of depression and anxiety are some of the most salient factors associated with quality-of-life outcomes.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Aged
  • Anxiety Disorders / epidemiology*
  • Anxiety Disorders / therapy
  • Cognition Disorders / diagnosis
  • Cognition Disorders / epidemiology
  • Cognitive Behavioral Therapy / methods
  • Comorbidity
  • Cost of Illness
  • Depression / epidemiology*
  • Depression / therapy
  • Female
  • Humans
  • Male
  • Neuropsychological Tests
  • Pulmonary Disease, Chronic Obstructive / epidemiology*
  • Pulmonary Disease, Chronic Obstructive / psychology*
  • Quality of Life / psychology*
  • Severity of Illness Index
  • Surveys and Questionnaires