Periodontal disease and gestational diabetes mellitus

Am J Obstet Gynecol. 2006 Oct;195(4):1086-9. doi: 10.1016/j.ajog.2006.06.035. Epub 2006 Jul 17.


Objective: We examined the relationship between periodontal disease and different types of diabetes in pregnant and nonpregnant women.

Study design: This study was based on the data from the third National Health and Nutrition Examination Survey (NHANES III), including 256 pregnant and 4234 nonpregnant women. Women were classified into those with gestational diabetes mellitus (GDM) in current pregnancy, with GDM in previous pregnancy, and with type 1 or 2 diabetes.

Results: In pregnant women, the prevalence of periodontitis was 44.8% in women with GDM and 13.2% in nondiabetic women, with adjusted odds ratio (aOR) of 9.11 (95% confidence interval [CI] 1.11-74.9). In nonpregnant women, the prevalence of periodontitis was 40.3% in women with type 1 or 2 diabetes, 25.0% in women with previous history of GDM, and 13.9% in nondiabetic women, with aOR of 2.76 (1.03-7.35) for women with type 1 or 2 diabetes.

Conclusion: We found an association between periodontal disease and GDM.

MeSH terms

  • Adolescent
  • Adult
  • Diabetes Complications / epidemiology
  • Diabetes Complications / etiology*
  • Diabetes, Gestational*
  • Female
  • Humans
  • Periodontitis / epidemiology
  • Periodontitis / etiology*
  • Pregnancy
  • Prevalence