Winter birth in association with a risk of brain tumor among a Finnish patient population

Neuroepidemiology. 2006;27(2):57-60. doi: 10.1159/000094578. Epub 2006 Jul 14.


The aim of this study was to analyze whether winter birth is related to risk of brain tumor in a clinical sample of patients from northern Finland. The study group comprised 101 patients suffering from a primary brain tumor. When comparing births in winter to births in other seasons, a 1.39-fold (95% CI 1.01-1.77) excess of winter births among patients was observed compared to respective births in the general population (p = 0.026). Especially patients with pituitary adenomas exhibited a 2.5-fold (95% CI 1.5-4.4) excess of winter births. The authors conclude that the season-of-birth effect in brain tumor patients should not be neglected when the actual and important tumorigenesis is investigated.

MeSH terms

  • Adult
  • Aged
  • Brain Neoplasms / epidemiology*
  • Brain Neoplasms / pathology
  • Climate
  • Female
  • Finland / epidemiology
  • Functional Laterality / physiology
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Parturition
  • Seasons*
  • Socioeconomic Factors
  • Tomography, X-Ray Computed