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. 2006 Aug;7(8):655-60.
doi: 10.1038/nrg1917.

The Chromosome Number in Humans: A Brief History


The Chromosome Number in Humans: A Brief History

Stanley M Gartler. Nat Rev Genet. .


Following the rediscovery of Mendel's work in 1900, the field of genetics advanced rapidly. Human genetics, however, lagged behind; this was especially noticeable in cytogenetics, which was already a mature discipline in experimental forms in the 1950s. We did not know the correct human chromosome number in 1955, let alone were we able to detect a chromosomal abnormality. In 1956 a discovery was reported that markedly altered human cytogenetics and genetics. The following is an analysis of that discovery.

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