[Clinical characteristics of pulmonary hypertension patients in two reference centers in the city of Sao Paulo]

Rev Assoc Med Bras (1992). 2006 May-Jun;52(3):139-43. doi: 10.1590/s0104-42302006000300012. Epub 2006 Jul 10.
[Article in Portuguese]


Objectives: Describe the clinical profile of PH patients from two pulmonary hypertension centers.

Methods: Retrospective chart analysis.

Results: One hundred and twenty three PH patients were included in the study; 62% of these presented functional class III or IV (NYHA). Mean right ventricle systolic pressure (RVSP) was 83.48+/-24.61 mmHg. There was no correlation between functional class and RVSP. About 50% of the patients were diagnosed as IPAH; 30% as pulmonary hypertension associated to schistosomiasis; 10% as PH associated to connective tissue diseases. Mean time of dyspnea until diagnosis was variable with no correlation with functional class (p>0.05). No difference was found in the clinical presentation in spite of the diverse etiologies.

Conclusion: Based upon our findings, we stressed the need for an active investigation of PH patients prior to administration of any therapeutic alternative. We emphasized that a better understanding of PH related to schistosomiasis is needed due to the high prevalence of this condition among PH patients as shown in the Brazilian population.

Publication types

  • English Abstract
  • Multicenter Study

MeSH terms

  • Adult
  • Brazil / epidemiology
  • Connective Tissue Diseases / complications
  • Echocardiography
  • Female
  • Humans
  • Hypertension, Pulmonary* / epidemiology
  • Hypertension, Pulmonary* / etiology
  • Hypertension, Pulmonary* / physiopathology
  • Male
  • Middle Aged
  • Prevalence
  • Retrospective Studies
  • Schistosomiasis / complications
  • Severity of Illness Index
  • Ventricular Dysfunction, Right / physiopathology