Comment
doi: 10.1016/j.immuni.2006.07.005.
Signaling in the immunological synapse: defining the optimal size
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- PMID: 16860751
- DOI: 10.1016/j.immuni.2006.07.005
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Comment
Signaling in the immunological synapse: defining the optimal size
Immunity.
2006 Jul.
Free article
Abstract
In this issue of Immunity, Varma et al. (2006) report that in the synapses between T cells and planar bilayers, T cell receptor (TCR) proximal signaling takes place in peripheral TCR-microclusters that form continually and that TCR signaling ceases when they fuse with the central supramolecular activation cluster.
Comment on
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T cell receptor-proximal signals are sustained in peripheral microclusters and terminated in the central supramolecular activation cluster.Immunity. 2006 Jul;25(1):117-27. doi: 10.1016/j.immuni.2006.04.010. Immunity. 2006. PMID: 16860761 Free PMC article.
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