Four X-chromosomal STRs and their allele frequencies in a Chinese population

W M Tang; K Y To

doi:10.1016/j.forsciint.2006.06.018

Four X-chromosomal STRs and their allele frequencies in a Chinese population

Forensic Sci Int. 2006 Oct 16;162(1-3):64-5. doi: 10.1016/j.forsciint.2006.06.018. Epub 2006 Jul 24.

Authors

W M Tang¹, K Y To

Affiliation

¹ Forensic Science Division, Hong Kong Government Laboratory, Homantin Government Offices, 88 Chung Hau Street, Kowloon, Hong Kong SAR, China. wmtang@govtlab.gov.hk

PMID: 16860957
DOI: 10.1016/j.forsciint.2006.06.018

Abstract

X-chromosomal markers are particularly useful for solving complex problems relating to kinship and deficiency paternity analysis. In the present study, population genetics data of four X-chromosomal short tandem repeats (STRs) DXS8378, HPRTB, DXS7423 and DXS7132 were obtained by analyzing 500 unrelated Chinese individuals (250 males and 250 females). Population genetics data obtained from the Chinese were compared with those of the Asian and European population. Mutations in X-chromosomal markers were analyzed based on a total of 61 proven father-child and 45 proven mother-child pairs.

MeSH terms

Chromosomes, Human, X*
DNA Fingerprinting
Female
Gene Frequency*
Genetics, Population*
Hong Kong
Humans
Male
Polymerase Chain Reaction
Tandem Repeat Sequences*