Minimally invasive endoscopic resection of sinonasal malignancies and skull base surgery

Acta Otolaryngol. 2006 Sep;126(9):981-6. doi: 10.1080/00016480600606780.

Abstract

Conclusions: Sinonasal malignancies without far lateral extension, intracranial invasion or orbital infiltration can be safely excised and reconstructed endoscopically with a satisfactory outcome.

Objectives: To evaluate the safety and efficacy of strictly endoscopic resection of malignant sinonasal neoplasms.

Patients and methods: Seven patients with sinonasal malignancies had received a minimally invasive endoscopic resection. Among them, two cases invaded the skull base. All patients were operated with curative intent.

Results: All the tumors were removed successfully by strictly endoscopic surgery. Two patients who had invasion of the skull base (28.6%) accepted postoperative radiotherapy. No complications associated with the operation occurred. The patients were followed up for 15-57 months (average 36.4 months). No local recurrence was noted in this series to date. The disease-free survival rate was 100% at a mean follow-up duration of 36.4 months.

MeSH terms

  • Adult
  • Aged
  • Carcinoma / pathology
  • Carcinoma / surgery
  • Disease-Free Survival
  • Endoscopy*
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Minimally Invasive Surgical Procedures
  • Neoplasm Invasiveness
  • Paranasal Sinus Neoplasms / pathology
  • Paranasal Sinus Neoplasms / surgery*
  • Sarcoma / pathology
  • Sarcoma / surgery
  • Skull Base Neoplasms / pathology
  • Skull Base Neoplasms / radiotherapy
  • Skull Base Neoplasms / surgery*