The Frequency of Fim Genes Among Salmonella Serovars

Microb Pathog. 1991 Jun;10(6):487-92. doi: 10.1016/0882-4010(91)90115-q.

Abstract

Salmonella serovars were examined for the presence of fim gene sequences using specific DNA probes. All strains, regardless of their ability to express surface-associated fimbriae, retain a considerable amount of DNA homologous to the gene probes used. The phenotypically nonfimbriae FIRN and non-FIRN strains of S. typhimurium retain detectable amounts of fim gene sequences and, therefore, may not be genotypically non-fimbriate. The MS adhesin can be expressed by type 2 fimbriate bacteria when they are transformed with discrete regions of the fim gene cluster. However, this conversion to a hemagglutinating phenotype is not associated with a small region of DNA. Therefore, the inability of type 2 fimbria-producing strains of Salmonella to mediate hemagglutination does not appear to be due to a small deletion in a single fim gene.

MeSH terms

  • Adhesins, Bacterial*
  • Bacterial Adhesion / genetics*
  • Bacterial Proteins / genetics*
  • Blotting, Southern
  • Chromosome Mapping
  • DNA Probes
  • Escherichia coli / genetics
  • Fimbriae, Bacterial / physiology*
  • Gene Expression Regulation, Bacterial
  • Genetic Variation
  • Hemagglutinins / genetics*
  • Salmonella / genetics*
  • Salmonella typhimurium / genetics
  • Serotyping
  • Transformation, Genetic

Substances

  • Adhesins, Bacterial
  • Bacterial Proteins
  • DNA Probes
  • Hemagglutinins
  • adhesin, Salmonella