A programme of symptom management for improving quality of life and drug adherence in AIDS/HIV patients

J Adv Nurs. 2006 Jul;55(2):169-79. doi: 10.1111/j.1365-2648.2006.03902.x.

Abstract

Aim: This paper reports an evaluation of the effect of symptom management programmed on drug adherence, CD4 count and virus load and the quality of life of patients with HIV/AIDS.

Background: Patients with HIV/AIDS have to face the long-term side effects caused by highly active antiretroviral therapy regimens. There has been little research to evaluate the influence of drug intervention side effects on self-care.

Methods: Sixty-seven patients with HIV/AIDS were randomly assigned to one-on-one teaching, group teaching, or control groups. All those in the one-on-one and group teaching groups attended a symptom management programme once a week, followed by 3 weeks of continuity and telephone counselling. Those in the control group were offered experimental intervention at the conclusion of data collection. The Customized Adherence Self-Report Questionnaire, CD4 count and virus load, and Quality of Life Index were used to evaluate the effectiveness of the symptom management programme before and at 3 months after the intervention.

Results: Median differences on the Customized Adherence Self-Report Questionnaire, CD4 count and virus load, and quality of life in both experimental groups were statistically significantly better than in the control group.

Conclusions: The symptom management programme can increase self-care ability in managing medication side effects in patients with HIV/AIDS.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acquired Immunodeficiency Syndrome / drug therapy
  • Acquired Immunodeficiency Syndrome / psychology
  • Adult
  • Antiretroviral Therapy, Highly Active / adverse effects*
  • CD4 Lymphocyte Count
  • Counseling / methods
  • Female
  • Group Processes
  • HIV Infections / drug therapy
  • HIV Infections / psychology*
  • Humans
  • Male
  • Patient Compliance / psychology*
  • Patient Education as Topic / methods
  • Quality of Life / psychology*
  • Self Care
  • Viral Load