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Review
, 25 (5), 711-5

Megestrol Acetate for the Palliation of Anorexia in Advanced, Incurable Cancer Patients

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Review

Megestrol Acetate for the Palliation of Anorexia in Advanced, Incurable Cancer Patients

Farrah Mateen et al. Clin Nutr.

Abstract

Anorexia, or loss of appetite, is a troubling symptom for many patients with advanced cancer. The early observation that breast cancer patients, who were prescribed megestrol acetate as a cancer treatment, went on to increase their appetite and gain weight has given rise to a large number of clinical trials that have tested this progestational drug as a palliative agent for the cancer anorexia/weight loss syndrome. This review focuses on these trials, summarizing their findings and providing a practical approach for prescribing megestrol acetate to advanced cancer patients who suffer from the cancer anorexia/weight loss syndrome.

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