Thermal and acid-catalyzed Hofmann-Martius rearrangement of 3-N-aryl-2-oxindoles into 3-(arylamino)-2-oxindoles

Philip Magnus; Rachel Turnbull

doi:10.1021/ol061191z

Thermal and acid-catalyzed Hofmann-Martius rearrangement of 3-N-aryl-2-oxindoles into 3-(arylamino)-2-oxindoles

Org Lett. 2006 Aug 3;8(16):3497-9. doi: 10.1021/ol061191z.

Authors

Philip Magnus¹, Rachel Turnbull

Affiliation

¹ Department of Chemistry and Biochemistry, University of Texas at Austin, 1 University Station A5300, Austin, Texas 78712-1167, USA. p.magnus@mail.utexas.edu

PMID: 16869644
DOI: 10.1021/ol061191z

Abstract

[reaction: see text] The Hofmann-Martius rearrangement of 3-N-aryl-2-oxindoles into 3-(arylamino)-2-oxindoles under thermal and acid-catalyzed conditions is described.

Publication types

Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

Catalysis
Crystallography, X-Ray
Hot Temperature
Indoles / chemistry*
Molecular Conformation
Molecular Structure

Substances

Indoles

Grants and funding

CA R01 50512/CA/NCI NIH HHS/United States