Meiotic crossing-over: obligation and interference

Cell. 2006 Jul 28;126(2):246-8. doi: 10.1016/j.cell.2006.07.010.


During meiosis, crossing-over--the exchange of genetic material between maternal and paternal chromosomes--is stringently controlled to restrict the number of crossovers per chromosome pair. In this issue of Cell, Martini et al., (2006) report that the reduction of crossover-initiating events does not result in fewer crossovers. These results have important implications for our understanding of crossover control.

Publication types

  • Comment

MeSH terms

  • Crossing Over, Genetic*
  • Homeostasis*
  • Meiosis*
  • Saccharomyces cerevisiae / genetics*
  • Saccharomyces cerevisiae / physiology*