Familial oral lichen planus: presentation of six families

Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006 Aug;102(2):e12-5. doi: 10.1016/j.tripleo.2006.03.016. Epub 2006 Jun 6.

Abstract

Objective: To present a series of 13 different cases of oral lichen planus (OLP) in 6 different families.

Study design: From 249 lichen planus cases, we found 13 that could be considered to be family related. A study of these 13 cases of OLP was carried out across the various generations, and the means of presentation, placement, and injuries were studied, as well as signs and symptoms.

Results: The predominant affectation was in the women; only 2 patients were male. The mothers showed predominance toward erythematous OLP with greater symptoms, and in their children, symptom-free white OLP was predominant.

Conclusions: It seems there may be some genetic predisposition toward OLP.

MeSH terms

  • Adult
  • Aged
  • Family Health
  • Female
  • Genetic Predisposition to Disease
  • Humans
  • Lichen Planus, Oral / genetics*
  • Male
  • Middle Aged