The management of lobular carcinoma in situ (LCIS). Is LCIS the same as ductal carcinoma in situ (DCIS)?

Eur J Cancer. 2006 Sep;42(14):2205-11. doi: 10.1016/j.ejca.2006.03.019. Epub 2006 Jul 28.


Lobular carcinoma in situ was first described over 60 years ago. Despite the long history, it continues to pose significant difficulties in screening, diagnosis, management and treatment. This is partly due its multi-focal and bilateral presentation, an incomplete understanding of its biology and natural history and perpetuation of misconceptions gathered over the last decades. In this review, the working group on behalf of EUSOMA has attempted to summarise the current thinking and management of this interesting lesion.

Publication types

  • Review

MeSH terms

  • Adult
  • Breast Neoplasms* / diagnosis
  • Breast Neoplasms* / therapy
  • Carcinoma in Situ* / diagnosis
  • Carcinoma in Situ* / therapy
  • Carcinoma, Ductal, Breast* / diagnosis
  • Carcinoma, Ductal, Breast* / therapy
  • Carcinoma, Lobular* / diagnosis
  • Carcinoma, Lobular* / therapy
  • Female
  • Humans
  • Middle Aged