Targeting Drosophila eye development

Genome Biol. 2006;7(7):226. doi: 10.1186/gb-2006-7-7-226.

Abstract

In order to understand the role of transcription factors in particular developmental processes it is necessary to know their target genes. A combination of bioinformatics, comparative expression profiling and microarray-based epistasis experiments has recently identified new targets of Eyeless, a key transcription factor in Drosophila retinal determination.

Publication types

  • Review

MeSH terms

  • Animals
  • Drosophila / genetics
  • Drosophila / growth & development*
  • Eye / growth & development*
  • Gene Expression Profiling
  • Oligonucleotide Array Sequence Analysis
  • RNA Interference
  • Transcription Factors / physiology

Substances

  • Transcription Factors