In Denmark, it was agreed to lower the Salmonella prevalence in pork to 1.2% before the end of 2006. The current control did not seem to be sufficient to attain this goal. Therefore, four alternatives to the existing Danish control strategy for Salmonella in pork were compared in a cost-benefit analysis: (1) hot-water decontamination of all pigs at slaughter, (2) sanitary slaughter of pigs from herds with high levels of Salmonella, (3) use of home-mixed feed in herds with slaughter pigs and (4) use of acidified feed for slaughter pigs. The data originated from official statistics, published papers as well as expert opinion. The partial cost-benefit analysis was restricted to slaughterhouses affiliated with the Danish Meat Association and Danish human cases ascribable to pork from these slaughterhouses. Only hot-water decontamination was socio-economically profitable. Hot-water decontamination had a net present value over 15 years of 3.5 million euros. For sanitary slaughter the net present value was - 43.6 million euros, for home-mixed feed it was - 262.3 million euros and for acidified feed it was - 79.9 million euros. For all alternatives the costs were born solely by the pig sector, whereas primarily the consumers and public authorities received the benefits. The conclusions were robust in sensitivity analyses.