Questioning INS VNTR Role in Obesity and Diabetes: Subclasses Tag IGF2-INS-TH Haplotypes; And -23HphI as a STEP (Splicing and Translational Efficiency Polymorphism)

Physiol Genomics. 2006 Dec 13;28(1):113. doi: 10.1152/physiolgenomics.00126.2006. Epub 2006 Aug 1.

Publication types

  • Comment
  • Letter

MeSH terms

  • Blood Glucose / metabolism
  • Deoxyribonucleases, Type II Site-Specific
  • Diabetes Mellitus, Type 2 / genetics*
  • Diabetes Mellitus, Type 2 / metabolism
  • Haplotypes
  • Humans
  • Insulin / genetics*
  • Insulin / metabolism
  • Insulin-Like Growth Factor II
  • Male
  • Minisatellite Repeats*
  • Obesity / genetics*
  • Obesity / metabolism
  • Polymorphism, Genetic*
  • Protein Biosynthesis
  • Proteins / genetics*
  • Proteins / metabolism
  • RNA Splicing
  • Tyrosine 3-Monooxygenase / genetics

Substances

  • Blood Glucose
  • IGF2 protein, human
  • Insulin
  • Proteins
  • Insulin-Like Growth Factor II
  • Tyrosine 3-Monooxygenase
  • Deoxyribonucleases, Type II Site-Specific
  • GGTGA-specific type II deoxyribonucleases