TXR1-mediated thrombospondin repression: a novel mechanism of resistance to taxanes?

Genes Dev. 2006 Aug 1;20(15):1975-81. doi: 10.1101/gad.1460806.
No abstract available

Publication types

  • Review

MeSH terms

  • Antineoplastic Agents / pharmacology*
  • Apoptosis / drug effects
  • Bridged-Ring Compounds / pharmacology*
  • Drug Resistance, Neoplasm*
  • Gene Expression Regulation, Neoplastic / physiology*
  • Humans
  • Male
  • Prostatic Neoplasms / drug therapy
  • Prostatic Neoplasms / genetics*
  • Prostatic Neoplasms / pathology
  • Repressor Proteins / physiology*
  • Taxoids / pharmacology*
  • Thrombospondin 1 / genetics
  • Thrombospondin 1 / metabolism*

Substances

  • Antineoplastic Agents
  • Bridged-Ring Compounds
  • PRR13 protein, human
  • Repressor Proteins
  • Taxoids
  • Thrombospondin 1
  • taxane