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. 2006 May;20(10):449-50, 453.

[The Measuring of ECP and IgE in Middle Ear Effusion of Patients With Otitis Media of Effusion]

[Article in Chinese]
Affiliations
  • PMID: 16883790

[The Measuring of ECP and IgE in Middle Ear Effusion of Patients With Otitis Media of Effusion]

[Article in Chinese]
Junhai Tian et al. Lin Chuang Er Bi Yan Hou Ke Za Zhi. .

Abstract

Objective: To study the relationship between otitis media of effusion (OME) and allergy by investigating eosinophil cationic protein in middle ear effusion ( MECP), middle ear effusion IgE (MIgE) and serum eosinophil cationic protein (SECP).

Method: The specimens drawn from 31 patients of OME were tested with Uni-CAP-100 allergic antigen testing system for the MECP, IgE and SECP. The results then were analyzed by statistical methods.

Result: MECP were found in all the effusion specimens of 31 patients, the average concentration of which was 56.88 microg/L. The MECP concentration level in nine specimens (28.1%) was significantly elevated. The average concentration of MIgE was 27.2 ku/L. The MIgE concentration level in three specimens (9.7%) was remarkably increased. There was a positive correlation between the MECP level and the MIgE level( P <0.05). The average concentration of SECP was 5.6 microg/L.

Conclusion: ECP exists in the middle ear effusion of OME. OME is an allergic inflammatory process more localized in middle ear itself in some patients. There may be a complicated allergic mechanism in OME.

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