[Effects of 33% grapefruit extract on the growth of the yeast--like fungi, dermatopytes and moulds]

Wiad Parazytol. 2001;47(4):845-9.
[Article in Polish]


Grapefruit seed extract was discovered by Jacob Harich an american immunologist in 1980. Assessment of the influence of grapefruit extract on the yeast-like fungi strains--Candida albicans growth. Material used in this investigation was ATCC test Candida albicans strains no 10231, 200 of Candida albicans strains, 5 of Candida sp. strains isolated from patients with candidiasis symptoms from different ontocenosis and 12 of dermatophytes and moulds isolated from patients. The susceptibility of the Candida was determined by serial dilution method. It seems that 33% grapefruit extract exert a potent antifungal activity against the yeast like fungi strains and had low activity against dermatophytes and moulds. Further studies in vitro and in vivo on greater number of the yeast-like fungi strains and other fungi species are needed.

MeSH terms

  • Arthrodermataceae / drug effects*
  • Arthrodermataceae / growth & development
  • Candida / drug effects*
  • Candida / growth & development
  • Cells, Cultured
  • Citrus paradisi*
  • Fungi / drug effects
  • Fungi / growth & development
  • Microbial Sensitivity Tests
  • Mycological Typing Techniques
  • Plant Extracts / pharmacology*
  • Plants, Medicinal / microbiology


  • Plant Extracts