Abstract
The safety and preliminary efficacy of trigeminal nerve stimulation (TNS) for epilepsy was evaluated in a pilot feasibility study of transcutaneous stimulation of the infraorbital and supraorbital branches of the trigeminal nerve. TNS was well tolerated. Four (57%) of seven subjects who completed >or=3 months experienced a >or=50% reduction in seizure frequency. The results of this pilot study support further investigation into the safety and efficacy of TNS for epilepsy.
Publication types
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Clinical Trial
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Comparative Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Adolescent
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Adult
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Aged
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Anticonvulsants / therapeutic use
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Electric Stimulation Therapy / adverse effects
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Electric Stimulation Therapy / methods*
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Epilepsy / drug therapy
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Epilepsy / prevention & control
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Epilepsy / therapy*
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Face / innervation
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Feasibility Studies
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Functional Laterality / physiology
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Humans
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Medical Records / statistics & numerical data
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Middle Aged
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Monitoring, Ambulatory
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Pilot Projects
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Treatment Outcome
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Trigeminal Nerve / physiology*