Targeted cancer therapeutics: the heartbreak of success

Nat Med. 2006 Aug;12(8):881-2. doi: 10.1038/nm0806-881.
No abstract available

Publication types

  • Comment
  • News

MeSH terms

  • Antibodies, Monoclonal / therapeutic use
  • Antineoplastic Agents / therapeutic use*
  • Benzamides
  • Drug Delivery Systems / methods*
  • Enzyme Inhibitors / adverse effects
  • Enzyme Inhibitors / therapeutic use
  • Heart Failure / chemically induced
  • Heart Failure / physiopathology
  • Humans
  • Imatinib Mesylate
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive / therapy
  • Models, Biological
  • Neoplasms / drug therapy
  • Neoplasms / therapy*
  • Piperazines / therapeutic use
  • Piperazines / toxicity
  • Pyrimidines / therapeutic use
  • Pyrimidines / toxicity
  • Ventricular Dysfunction, Left / chemically induced
  • Ventricular Dysfunction, Left / physiopathology
  • src-Family Kinases / adverse effects
  • src-Family Kinases / antagonists & inhibitors

Substances

  • Antibodies, Monoclonal
  • Antineoplastic Agents
  • Benzamides
  • Enzyme Inhibitors
  • Piperazines
  • Pyrimidines
  • Imatinib Mesylate
  • src-Family Kinases